Leibniz Institute for Polymer Research Dresden

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45. Felix Wong, Erica J. Zheng, Jacqueline Valeri, Nina Donghia, Melis Anahtar, Satotaka Omori, Alicia Li, Andrés Cubillos-Ruiz, Aarti Krishnan, Wengong Jin, Abigail Manson, Jens Friedrichs, Ralf Helbig, Behnoush Hajian, Dawid Fiejtek, FlorenceWagner, Holly Soutter, Ashlee Earl, Jonathan Stokes, Lars D. Renner, James J. Collins. Discovery of a structural class of antibiotics with explainable deep learning. Nature, 2024.

44. Erica J. Zheng, Jacqueline A. Valeri, Ian W. Andrews, Felix Wong, Jonathan M. Stokes, Lars D. Renner, James J. Collins. Discovery of antibiotics that selectively kill metabolically dormant bacteria. Cell Chemical Biology, 2024, 31, 1-17.

43. Wei Mao, Lars D. Renner, Charlene Cornilleau, Ines Li de la Sierra-Gallay, Sana Afensiss, Sarah Benlamara, Yoan Ah-Seng, Herman Van Tilbeurgh, Sylvie Nessler, Aurelie Bertin, Arnaud Chastanet, Rut Carballido-Lopez. On the role of nucleotides and lipids in the polymerization of the actin homolog MreB from a Gram-positive bacterium. eLife, 2023, 12, e84505.

42. Juliane Valtin, Stephan Behrens, Andre Ruland, Florian Schmieder, Frank Sonntag, Lars D. Renner, Manfred F Maitz, and Carsten Werner. A New In Vitro Blood Flow Model for The Realistic Evaluation of Antimicrobial Surfaces. Advanced Healthcare Materials, 2023, 12, 2301300.

41. Enno R. Oldewurtel, Yuki Kitahara, Baptiste Cordier, Richard Wheeler, Gizem Özbaykal, Elisa Brambilla, Ivo Gomperts Boneca, Lars David Renner and Sven van Teeffelen. Cell envelope growth of Gram-negative bacteria proceeds independently of cell wall synthesis. The EMBO Journal, 2023, 42, e112168.

40. Jens Friedrichs, Ralf Helbig, Julia Hilsenbeck, Prithvi Raj Pandey, Jens-Uwe Sommer, Lars David Renner, Tilo Pompe, Carsten Werner. Entropic repulsion of cholesterol-containing layers counteracts bio-adhesion. Nature, 2023, 618, 733–739.

39. Barbara Schamberger, Andreas Roschger, Ricardo Ziege, Karine Anselme, Martine Ben Amar, Michał Bykowski, André PG Castro, Amaia Cipitria, Rhoslyn Coles, Rumiana Dimova, Michaela Eder, Sebastian Ehrig, Luis M Escudero, Myfanwy E Evans, Paulo R Fernandes, Peter Fratzl, Liesbet Geris, Notburga Gierlinger, Edouard Hannezo, Aleš Iglič, Jacob JK Kirkensgaard, Philip Kollmannsberger, Łucja Kowalewska, Nicholas A Kurniawan, Ioannis Papantoniou, Laurent Pieuchot, Tiago HV Pires, Lars David Renner, Andrew Sageman‐Furnas, Gerd E Schröder‐Turk, Anupam Sengupta, Vikas R Sharma, Antonio Tagua, Caterina Tomba, Xavier Trepat, Sarah L Waters, Edwina Yeo, Cécile M Bidan, John WC Dunlop. Curvature in biological systems: its quantification, emergence and implications across the scales. Advanced Materials, 2023, 35, 2206110.

38. Melissa K. L. N. Sikosana, André Ruland, Carsten Werner, Lars D. Renner. Combining microscopy assays of bacteria-surface interactions to better evaluate antimicrobial polymer coatings. Applied and Environmental Microbiology, 2022, 88, e02241-21.

37. Richard S. Muniz, Paul C. Campbell, Thomas E. Sladewski, Lars D. Renner, Christopher L. de Graffenried. Revealing spatio-temporal dynamics with long-term trypanosomatid live-cell imaging. PLoS Pathogens, 2022, 18, e1010218.

36. André Ruland, Saskia Schenker, Lucas Schirmer, Jens Friedrichs, Andrea Meinhardt, Véronique B Schwartz, Nadine Kaiser, Rupert Konradi, William MacDonald, Tina Helmecke, Melissa KLN Sikosana, Juliane Valtin, Dominik Hahn, Lars D Renner, Carsten Werner, Uwe Freudenberg. Amphiphilic Copolymers for Versatile, Facile, and In Situ Tunable Surface Biofunctionalization. Advanced Materials, 2021, 33, 2102489.

35. Felix Wong, Sean Wilson, Ralf Helbig, Smitha Hedge, Olga Aftenieva, Hai Zheng, Chenli Liu, Teuta Pilizota, Ethan C Garner, Ariel Amir and Lars D Renner. Understanding beta-lactam-induced lysis at the single-cell level. Frontiers in Microbiology, 2021, 12, 712007.

34. Felix Wong, Jonathan M Stokes, Bernardo Cervantes, Sider Penkov, Jens Friedrichs, Lars D Renner and James J Collins. Cytoplasmic condensation induced by membrane damage is associated with antibiotic lethality. Nature Communications, 2021, 12 (1), 1-15.

33. R Konradi, V Schwartz, M Seufert, LD Renner, U Freudenberg, C Werner. Devices for cultivating cells coated with a copolymer of polyethyleneglykol (meth) acrylate. 2020 US Patent App. 16/627,518

32. Ana L Cordeiro, Markus Rückel, Frank Bartels, Manfred F Maitz, Lars D. Renner and Carsten Werner. Protein adsorption dynamics to polymer surfaces revisited—A multisystems approach. Biointerphases, 2019, 14 (5), 051005.

31. Lars D. Renner. Engineering Bacterial Shape Using Soft Matter Microchambers. Current protocols in chemical biology, 2019, 11 (1), e59.

30. S. Hussain, C. N. Wivagg, P. Szwedziak, F. Wong, K. Schaefer, T. Izore, Lars D. Renner, M.J. Holmes, Y. Sun, A.W. Bisson-Filho, S. Walker, A. Amir, J. Löwe, and E. C. Garner. MreB filaments align along greatest principal membrane curvature to orient cell wall synthesis. eLIFE, 2018, 7, e32471.

29. S. Schulz, M. Maitz, S. Hänsel, Lars D. Renner, and C. Werner. Analyzing the antiseptic capacity of silver-functionalized poly(ethylene glycol)-heparin hydrogels after human whole blood exposure. Biomaterials Science, 2018, 6, 1129-1139.

28. S. van Teeffelen and Lars D. Renner. Recent advances in understanding how rod-like bacteria stably maintain their cell shapes. F1000Research, 2018, 7(F1000 Faculty Rev), 241.

27. J. Rossmann, Lars D. Renner, R. Oertel, A. El-Armouche. Post-column infusion of internal standard quantification for liquid chromatography-electrospray ionization-tandem mass spectrometry analysis – Pharmaceuticals in urine as example approach. J Chrom A, 2018, 1535, 80–87.

26. Y.-J. Eun, P.-Y. Ho, M. Kim, S. LaRussa, L. Robert, Lars D. Renner, A. Schmid, E. Garner, and A. Amir. Archaeal cells share common size control with bacteria despite noisier growth and division. Nature Microbiology, 2018, 3, 148-154.

25. F. Wong, Lars D. Renner, G. Özbaykal, J. Paulose, D.B. Weibel, S. van Teeffelen and A. Amir. Mechanical strain sensing implicated in cell shape recovery in Escherichia coli. Nature Microbiology, 2017, 2, 17115.

24. Lars D. Renner, J. Zan, L. I. Hu, M. Martinez, P. J. Resto, A. Siegel, C. Torres, S. B. Hall, T. R. Slezak, T. H. Nguyen, D. B. Weibel. Detection of ESKAPE bacterial pathogens at the point of care using isothermal DNA-based assays in a portable degas-actuated microfluidic diagnostic assay platform. Applied Environmental Microbiology, 2017, 83, e02449-16.

23. J. Rossmann, R. Gurke, S. Schubert, Lars D. Renner, R. Oertel, W. Kirch. Evaluation of the matrix effect of different sample matrices for 33 pharmaceuticals by post-column infusion. J Chrom B, 2015, 1000, 84–94.

22. A. Gang, G. G. Garriga, Lars D. Renner, L. Baraban, G. Cuniberti. A simple two-step silane-based (bio) receptor molecule immobilization method without additional binding site passivation. RCS Advances, 2015, 5, 35631–35634.

21. C. Schmaedicke, M. Poetschke, Lars D. Renner, L. Baraban, M. Bobeth, and G. Cuniberti. Copper nanowires synthesis by directed electrochemical nanowire assembly. RSC Advances, 2014, 4, 46363–46368.

20. L.D. Renner, P. Eswaramoorthy, K. S. Ramamurthi, and D. B. Weibel. Studying biomolecule localization by engineering bacterial cell wall curvature. PLoS One, 2013, 8, e84143.

19. C. Schmaedicke, A. Nerowski, L. Baraban, L.D. Renner and G. Cuniberti. Fabrication of Copper Nanowires from Aqueous Solution. Proceedings of the AMA Conferences, 2013.

18. L.D. Renner and D.B.Weibel. MinD and MinE Interact with Anionic Phospholipids and Regulate Division Plane Formation in Escherichia coli. J Biol Chem, 2012, 287, 38835–38844.

17. R. Zimmermann, D. Kuettner, L. Renner, M. Kaufmann, and C. Werner. Fluidity modulation of phospholipid bilayers by electrolyte ions: Insights from fluorescence microscopy and microslit electrokinetic experiments. J Phys Chem. A, 2012, 116, 6519-6525.

16. H.H. Tuson, G.K. Auer, L.D. Renner, M. Hasebe, M. Salick, W.C. Crone, A. Gopinathan, KC. Huang, and D.B. Weibel. Measuring the stiffness of bacterial cells from growth rates in hydrogels of tunable elasticity. Mol. Microbiol, 2012, 84, 874–891.

15. H.H. Tuson, L.D. Renner, and D.B.Weibel. Polyacrylamide hydrogels as substrates for studying bacteria. Chem. Commun, 2012, 48, 1595–1597.

14. T. Pompe, M. Kaufmann, M. Kasimir, S. Johne, S. Glorius, L. Renner, M. Bobeth, W. Pompe and C. Werner. Friction-Controlled Traction Force in Cell Adhesion. Biophys J. 2011, 101, 1863–1870.

13. L.D. Renner and Douglas B. Weibel. Cardiolipin microdomains localize to negatively curved regions of Escherichia coli membranes. Proc Natl Acad Sci USA. 2011, 108, 6264–6269.

12. L.D. Renner and Douglas B. Weibel. Physicochemical regulation of biofilm formation. MRS Bulletin. 2011, 36, 347–355.

11. L. Renner, T. Pompe, R. Lemaitre, D. Drechsel, and C. Werner. Controlled enhancement of transmembrane enzyme activity in polymer cushioned supported bilayer membranes. Soft Matter. 2010, 6, 5382–5389.

10. M. Kaufmann, Y. F. Jia, L. Renner, S. Gupta, D. Kuckling, C. Werner and T. Pompe. Tuneable swelling of thermo- and pH-responsive copolymer films. Soft Matter. 2010, 6, 937–944.

9. R. Zimmermann, D. Kuettner, L. Renner, M. Kaufmann, J. Zitzmann, M. Mueller and C.Werner. Charging and structure of zwitterionic supported bilayer lipid membranes studied by streaming current measurements, fluorescence microscopy, and attenuated total reflection Fourier transform infrared spectroscopy. Biointerphases. 2009, 4, 1–6.

8. L. Renner, T. Pompe, and C. Werner. Electrostatic stretching of grafted maleic acid copolymer chains. Express Polymer Letters. 2009, 3, 33–38.

7. L. Renner, T. Osaki, S. Chiantia, P. Schwille, T. Pompe, and C. Werner. Supported lipid bilayers on spacious and pH-responsive polymer cushions with varied hydrophilicity. J Phys Chem. B. 2008, 112, 6373–6378.

6. T. Osaki, L. Renner, M. Herklotz, C. Werner. Hydrophobic and electrostatic interactions in the adsorption of fibronectin at maleic acid copolymer films. J Phys Chem. B. 2006, 110, 12119– 12124.

5. T. Pompe, L. Renner, M. Grimmer, N. Herold, C. Werner. Functional films of maleic anhydride copolymers under physiological conditions. Macromol Biosci. 2005, 5, 890–895.

4. L. Renner, T. Pompe, K. Salchert, C. Werner. Fibronectin displacement at polymer surfaces. Langmuir. 2005, 21, 4571–4577.

3. T. Pompe, L. Renner, C. Werner. Nanoscale features of fibronectin fibrillogenesis depend on protein-substrate interaction and cytoskeleton structure. Biophys J. 2005, 88, 527–534.

2. L. Renner, B. Jorgensen, M. Markowski, K. Salchert, C. Werner, T. Pompe. Control of fibronectin displacement on polymer substrates to influence endothelial cell behaviour. J Mater Sci: Materials in Medicine. 2004, 15, 385–388.

1. L. Renner, T. Pompe, K. Salchert, C. Werner. Dynamic alterations of fibronectin layers on copolymer substrates with graded physicochemical characteristics. Langmuir. 2004, 20, 2928– 2933.