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Dr. Mikhail Tsurkan

Institute of Biofunctional Polymer Materials
+49 351 4658 1265 +49 351 4658 533

Mikhail Tsurkan PhD is the leader of the spin-off project TissueGUARD. The project TissueGUARD is part of the EXIST program and is funded by the German Federal Ministry for Economic Affairs and Energy (BMWi) and the European Social Fund (ESF) as well as the Leibniz Institute of Polymer Research Dresden (IPF) Germany.

Fields of work

The research is focused on the development of new Biofunctional Materials for the needs of regenerative therapies and stem cell research which includes:

  • Design and synthesis of peptide and carbohydrate conjugates for biomedical and biomaterial applications
  • Incorporation of biological active molecules into hydrogel materials through rational synthesis
  • Photochemical and photophysical developments for biofunctional materials applications
  • Development of bioanalytical methods for natural compounds and biopolymers characterization

Additional information

Publications

  • Ehrlich, H. ; Motylenko, M. ; Tsurkan, M. ; et al., Multiphase biomineralization: Enigmatic invasive siliceous diatoms produce crystalline calcite more Advanced Functional Materials 26 (2016) 2503-2510
  • Freudenberg, U. ; Zieris, A. ; Chwalek, K. ; Tsurkan, M. ; Maitz, M.F. ; Atallah, P. ; Levental, K. ; Eming, S. A. ; Werner, C. Heparin desulfation modulates VEGF release and angiogenesis in diabetic wounds more Journal of Controlled Release 220 (2015) 79-88
  • Newland, B. ; Welzel, P. ; Newland, H. ; Renneberg, C. ; Kolar, P. ; Tsurkan, M. ; Rosser, A. ; Freudenberg, U. ; Werner, C. Tackling cell transplantation anoikis: An injectable, shape memory cryogel microcarrier platform material for stem cell and neuronal cell growth more Small 11 (2015) 5047-5053
  • Wysokowski, M. ; Motylenko, M. ; Beyer, J. ; ..., ; Tsurkan, M. Extrem biomimetic approach for developing novel chitin-GeO2 nanocomposites with photoluminescent properties more Nano Research 8 (2015) 2288-2301
  • Tsurkan, M. ; Wetzel, R. ; Pérez-Hernández, H. ; Chwalek, K. ; Kozlova, A. ; Freudenberg, U. ; Kempermann, G. ; Zhang, Y. ; Lasagni, A. ; Werner, C. Photopatterning of multifunctional hydrogels to direct adult neural precursor cells more Advanced Healthcare Materials 4 (2015) 516-521
  • Thompson, M. ; Tsurkan, M. ; Chwalek, K. ; Bornhäuser, M. ; Schlierf, M. ; Werner, C. ; Zhang, Y. Self-assembling hydrogels crosslinked solely by receptor-ligand interactions: Tunability, rationalization of physical properties and 3D cell culture more Chemistry - A European Journal 21 (2015) 3178-3182
  • Zieris, A. ; Dockhorn, R. ; Röhrich, A. ; Zimmermann, R. ; Müller, M. ; Welzel, P. ; Tsurkan, M. ; Sommer, J.-U. ; Freudenberg, U. ; Werner, C. Biohybrid networks of selectively desulfated glycosaminoglycans for tunable growth factor delivery more Biomacromolecules 15 (2014) 4439-446
  • Anitha, A. ; Sowmya, S. ; Sudheesh Kumar, P. T. ; Deepthi, S. ; Chennazhi, K. P. ; Ehrlich, H. ; Tsurkan, M. ; Jayakumar, R. Chitin and chitosan in selected biomedical applications more Progress in Polymer Science 39 (2014) 1644-1667
  • Tsurkan, M. ; Chwalek, K. ; Schoder, M. ; Freudenberg, U. ; Werner, C. Chemoselective peptide functionalization of starPEG-GAG hydrogels more Bioconjugate Chemistry 25 (2014) 1942-1950
  • Nickerl, J. ; Tsurkan, M. ; Hensel, R. ; Neinhuis, C. ; Werner, C. The multi-layered protective cuticle of Collembola: a chemical analysis more Journal of the Royal Society Interface 11 (2014) 2014.0619
  • Chwalek, K. ; Tsurkan, M. ; Freudenberg, U. ; Werner, C. Glycosaminoglycan-based hydrogels to modulate heterocellular communication in in vitro angiogenesis models more Scientific Reports 4 (2014) Article number: 4414
  • Ehrlich, H. ; Rigby, J. K. ; Botting, J. ; Tsurkan, M. ; Werner, C. ; Schwille, P. ; Petrasek, Z. ; Pisera, A. ; Simon, P. ; Sivkov, V. N. ; Vyalikh, D. V. ; Molodtsov, S. L. ; Kurek, D. ; Kammer, M. ; Hunoldt, S. ; Born, R. ; Stawski, D. ; Steinhoff, B. Discovery of 505-million-year old chitin in the basal demosponge Vauxia gracilenta more Scientific Reports 3 (2013) 3497
  • Wysokowski, M. ; Bazhenov, V. V. ; Tsurkan, M. ; Galli, R. ; Stelling, A. ; Stöcker, H. ; Kaiser, S. ; Niederschlag, E. ; Gärtner, G. ; Behm, T. ; Ilan, M. ; Petrenko, A. Y. ; Jesionowski, T. ; Ehrlich, H. Isolation and identification of chitin in three-dimensional skeleton of aplysina fistularis marin sponge more International Journal of Biological Macromolecules 62 (2013) 94-100
  • Ehrlich, H. ; Kaluzhnaya, O. V. ; Brunner, E. ; Tsurkan, M. ; Ereskovsky, A. ; Ilan, M. ; Tabachnick, K. R. ; Bazhenov, V. V. ; Paasch, S. ; Kammer, M. ; Born, R. ; Stelling, A. ; Galli, R. ; Belikov, S. ; Petrova, O. V. ; Sivkov, V. N. ; Vyalikh, D. V. ; Identification and first insights into the structure and biosynthesis of chitin from the freshwater sponge Spongilla lacustris more Journal of Structural Biology 183 (2013) 474-483
  • Maitz, M.F. ; Freudenberg, U. ; Tsurkan, M. ; Fischer, M. ; Beyrich, T. ; Werner, C. Bio-responsive polymer hydrogels homeostatically regulate blood coagulation more Nature Communications 4 (2013) 7 Seiten [OPEN]
  • Ehrlich, H. ; Kaluzhnaya, O. V. ; Tsurkan, M. ; Ereskovsky, A. ; Tabachnick, K. R. ; Ilan, M. ; Stelling, A. ; Galli, R. ; Petrova, O. V. ; Nekipelov, S. V. ; Sivkov, V. N. ; Vyalikh, D. V. ; Born, R. ; Behm, T. ; Ehrlich, A. ; Chernogor, L. I. ; Belikov, First report on chitinous holdfast in sponges (Porifera) more Proceedings of the Royal Society B 280 (2013) 20130339
  • Tsurkan, M. ; Chwalek, K. ; Prokoph, S. ; Zieris, A. ; Levental, K. ; Freudenberg, U. ; Werner, C. Defined polymer-peptide conjugates to form cell-instructive star PEG-heparin matrices in situ more Advanced Materials 25 (2013) 2606-2610
  • Tsurkan, M. ; Hauser, P. V. ; Zieris, A. ; Carvalhosa, R. ; Bussolati, B. ; Freudenberg, U. ; Gamussi, G. ; Werner, C. Growth factor delivery from hydrogel particle aggregates to promote tubular regeneration after acute kidney injury more Journal of Controlled Release 167 (2013) 248-255
  • Wieduwild, R. ; Tsurkan, M. ; Chwalek, K. ; Murawala, P. ; Nowak, M. ; Freudenberg, U. ; Neinhuis, C. ; Werner, C. ; Zhang, Y. Minimal peptide motif for non-covalent peptide-heparin hydrogels more Journal of the American Chemical Society 135 (2013) 2919-2922
  • Chwalek, K. ; Levental, K. ; Tsurkan, M. ; Zieris, A. ; Freudenberg, U. ; Werner, C. Two-tier hydrogel degradation to boost endothelial cell morphogenesis more Biomaterials 32 (2011) 9649-9657
  • Ehrlich, H. ; Deutzmann, R. ; Brunner, E. ; Cappellini, E. ; Koon, H. ; Solazzo, C. ; Yang, Y. ; Ashford, D. ; thomas-Oates, J. ; Lubeck, M. ; Baessmann, C. ; Langrock, T. ; Hoffmann, R. ; Wörheide, G. ; Reitner, J. ; Simon, P. ; Tsurkan, M. ; Ereskovsky, Mineralization of the metre-long biosilica structures of glass sponges is templated on hydroxylated collagen more Nature Chemistry 2 (2010) 1084-1088
  • Ehrlich, H. ; Tsurkan, M. Mineralization of the metre-long biosilica structures of glass sponges is templated on hydroxylated collagen more Nature Chemistry 2 (2010) 1084-1088
  • Tsurkan, M. ; Chwalek, K. ; Levental, K. ; Freudenberg, U. ; Werner, C. Modular starPEG-heparin gels with bifunctional peptide linkers more Macromolecular Rapid Communications 31 (2010) 1529-1533
  • Tsurkan, M. ; Levental, K. ; Freudenberg, U. ; Werner, C. Enzymatically degradable heparin-polyethylene glycol gels with controlled mechanical properties more Chemical Communications 46 (2010) 1141-1143