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Dr. Mikhail Tsurkan

Institute of Biofunctional Polymer Materials
+49 351 4658 1265 +49 351 4658 533

Mikhail Tsurkan PhD is the leader of the spin-off project TissueGUARD. The project TissueGUARD is part of the EXIST program and is funded by the German Federal Ministry for Economic Affairs and Energy (BMWi) and the European Social Fund (ESF) as well as the Leibniz Institute of Polymer Research Dresden (IPF) Germany.

Fields of work

The research is focused on the development of new Biofunctional Materials for the needs of regenerative therapies and stem cell research which includes:

  • Design and synthesis of peptide and carbohydrate conjugates for biomedical and biomaterial applications
  • Incorporation of biological active molecules into hydrogel materials through rational synthesis
  • Photochemical and photophysical developments for biofunctional materials applications
  • Development of bioanalytical methods for natural compounds and biopolymers characterization

Additional information

Publications

  • Helmecke, T.; Hahn, D.; Ruland, A.; Tsurkan, M. V.; Maitz, M. F.; Werner, C. Adsorbed polymer conjugates to adaptively inhibit blood coagulation activation by medical membranes more Journal of Controlled Release 368 (2024) 344-354
  • Adepoju, F. O.; Sokolova, K. V.; Gette, I. F.; Danilova, I. G.; Tsurkan, M. V.; Mondragon, A. C.; Kovaleva, E. G.; Miranda, J. M. Protective effect of betulin on streptozotocin–nicotinamide-induced diabetes in female rats more International Journal of Molecular Sciences 25 (2024) 2166
  • Khalymbadzha, I. A.; Fatykhov, R. F.; Butorin, I. I.; Sharapov, A. D.; Potapova, A. P.; Muthipeedika, N. J.; Zyryanov, G. V.; Melekhin, V. V.; Tokhtueva, M. D.; Deev, S. L.; Kukhanova, M. K.; Mochulskaya, N. N.; Tsurkan, M. V. Bioinspired pyrano[2,3-f]chromen-8-ones: ring c-opened analogues of Calanolide A: synthesis and anti-HIV-1 evaluation more Biomimetics 9 (2024) 44
  • Helmecke, T.; Rose, I. I.; Tsurkan, M. V.; Roth, H.; Maitz, M. F.; Werner, C.; Wessling, M. Poly(styrene-alt-maleic anhydride)-copolymers blended in poly(ether sulfone) membranes as a platform for effective biomolecular surface functionalization more Journal of Membrane Science 689 (2024) 122050
  • Tsurkan, M. V.; Lohmeier, J.; Terrin, S.; Arndt, S.; Tsurkan, S. Assymetrical injector for endothelium-in DMEK without the need of pull-through technique more BMJ Open Ophthalmology 8 (2023) A8-A8
  • Pokharkar, O.; Zyryanov, G. V.; Tsurkan, M. V. Natural products from marine actinomycete genus Salinispora might inhibit 3CLpro and PLpro proteins of SARS-CoV-2: an in silico evidence more Microbiology Research 14 (2023) 1907-1941
  • Bertolin, M.; Barbaro, V.; Tsurkan, M.; Tsurkan, S.; Arndt, S.; Ponzin, D.; Ferrari, S. P16-A111 Factors affecting the density of corneal endothelial cell cultures obtained from donor corneas more BMJ Open Ophthalmology 8 (2023) A7
  • Pokharkar, O.; Anumolu, H.; Zyryanov, G. V.; Tsurkan, M. V. Natural products from red algal genus Laurencia as potential inhibitors of RdRp and nsp15 enzymes of SARS-CoV-2: an in silico perspective more Microbiology Research 14 (2023) 1020-1048
  • Pokharkar, O.; Lakshmanan, H.; Zyryanov, G. V.; Tsurkan, M. V. Antiviral potential of Antillogorgia americana and elisabethae natural products against nsp16–nsp10 complex, nsp13, and nsp14 proteins of SARS-CoV-2: an in silico investigation more Microbiology Research 14 (2023) 993-1019
  • Adepoju, F. O.; Duru, K. C.; Li, E.; Kovaleva, E. G.; Tsurkan, M. Pharmacological Potential of Betulin as a Multitarget Compound more Biomolecules 13 (2023) 1105
  • Sharapov, A. D.; Fatykhov, R. F.; Khalymbadzha, I. A.; Zyryanov, G. V.; Chupakhin, O. N.; Tsurkan, M. V. Plant coumarins with anti-HIV activity: isolation and mechanisms of action more International Journal of Molecular Sciences 24 (2023) 2839
  • Pokharkar, O. ; Lakshmanan, H. ; Zyryanov, G. ; Tsurkan, M. In silico evaluation of antifungal compounds from marine sponges against COVID-19-associated mucormycosis more Marine Drugs 20 (2022) 215
  • Kovalev, I. ; Taniya, O.S. ; Sadieva , L. K. ; Volkova, N.N. ; Minin , A. S. ; Grzhegorzhevskii, K. V. ; Gorbunov, E. B. ; Zyryanov, G. ; Chupakhin, O. ; Charushin , V. N. ; Tsurkan, M. Bola-type PAH-based fluorophores/chemosensors: Synthesis via an unusual clemmensen reduction and photophysical studies more Journal of Photochemistry and Photobiology A: Chemistry 420 (2021) 113466
  • Kovalev, I. ; Sadieva , L. K. ; Taniya, O.S. ; Yurk , V. M. ; Minin , A. S. ; Santra, S. ; Zyryanov, G. ; Charushin , V. N. ; Chupakhin, O. ; Tsurkan, M. Computer vision vs. spectrofluorometer-assisted detection of common nitro-explosive components with bola-type PAH-based chemosensors more RSC Advances 11 (2021) 25850-25857
  • Lee, Y. ; Bandari, V. K. ; Li, Z. ; Medina-Sánchez, M. ; Maitz, M.F. ; Karnaushenko, D. ; Tsurkan, M. ; Karnaushenko, D. D. ; Schmidt, O. G. Nano-biosupercapacitors enable autarkic sensor operation in blood more Nature Communications 12 (2021) 4967
  • Satish, L. ; Santra, S. ; Tsurkan, M. ; Werner, C. ; Jana, M. ; Sahoo, H. Conformational changes of GDNF-derived peptide induced by heparin, heparan sulfate, and sulfated hyaluronic acid - Analysis by circular dichroism spectroscopy and molecular dynamics simulation more International Journal of Biological Macromolecules 182 (2021) 2144-2150
  • Jaeschke, A. ; Harvey, N.R. ; Tsurkan, M. ; Werner, C. ; Griffiths, L.R. ; Haupt, L.M. ; Bray, L. Techniques for RNA extraction from cells cultured in starPEG-heparin hydrogels more Open Biology 11 (2021) 200388
  • Tsurkan, M. ; Voronkina, A. ; Khrunyk, Y.Y. ; Wysokowski, M. ; Petrenko, I. ; Ehrlich, H. Progress in chitin analytics more Carbohydrate Polymers 252 (2021) 117204
  • Talevski, T. ; Leshoska, A.T. ; Pejoski, E. ; Pejin, B. ; Machalowski, T. ; Wysokowski, M. ; Tsurkan, M. ; Petrova, O. V. ; Sivkov, V. N. ; Martinovic, R. ; Pantovic, S. ; Khrunyk, Y.Y. ; Trylis, V. ; Fursov, A. ; Djurovic, M. ; Jesionowski, T. ; Ehrlich, Identification and first insights into the structure of chitin from the endemic freshwater demosponge Ochridaspongia rotunda (Arndt, 1937) more International Journal of Biological Macromolecules 162 (2020) 1187-1194
  • Koch, K.M. ; Jaeschke, A. ; Murekatete, B. ; Ravichandran, A. ; Tsurkan, M. ; Werner, C. ; Soon, P. ; Hutmacher, D. W. ; Haupt, L.M. ; Bray, L. Stromal fibroblasts regulate microvascular-like network architecture in a bioengineered breast tumour angiogenesis model more Acta Biomaterialia 114 (2020) 256-269
  • Götze, J. ; Hofmann, B. ; Machalowski, T. ; Tsurkan, M. ; Jesionowski, T. ; Ehrlich, H. ; Kleeberg, R. ; Ottens, B. Biosignatures in subsurface filamentous fabrics (SFF) from the Deccan Volcanic Province, India more Minerals 10 (2020) 540
  • Nowacki, K. ; Stepniak, I. ; Langer, E. ; Tsurkan, M. ; Wysokowski, M. ; Petrenko, I. ; Khrunyk, Y.Y. ; Fursov, A. ; Bo, M. ; Bavestrello, G. ; Joseph, Y. ; Ehrlich, H. Electrochemical approach for isolation of chitin from the skeleton of the black coral. Cirrhipathes sp. (Antipatharia) more Marine Drugs 18 (2020) 297
  • Binnewerg, B. ; Schubert, M. ; Voronkina, A. ; Muzychka , L. ; Petrenko, I. ; Djurovic, M. ; Kovalchuk, V. ; Tsurkan, M. ; Bechmann, N. ; Fursov, A. ; Ivanenko, V.N. ; Smolii , O.B. ; Joseph, Y. ; Giovine, M. ; Bornstein, S. R. ; Stelling, A. ; Tunger, A Marine biomaterials: Biomimetic and pharmacological potential of cultivated Aplysina aerophoba marine demosponge more Materials Science and Engineering C - Materials for Biological Applications 109 (2020) 110566
  • Khrunyk, Y.Y. ; Belikov, S. ; Tsurkan, M. ; Vyalykh, I.V. ; Markaryan, A.Y. ; Karabanalov, M.S. ; Popov, A. A. ; Wysokowski, M. Surface-dependent osteoblasts response to TiO2 nanotubes of different crystallinity more Nanomaterials 10 (2020) 320
  • Schirmer, L. ; Chwalek, K. ; Tsurkan, M. ; Freudenberg, U. ; Werner, C. Glycosaminoglycan-based hydrogels with programmable host reactions more Biomaterials 228 (2020) 119557