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Dr. Uwe Freudenberg

Institute of Biofunctional Polymer Materials
+49 351 4658 408/ 573 +49 351 4658 533

Personal data

  • 2010-present: Speaker of the research area Matrix Engineering
  • 2007-present: Responsible for the division Biohybrid-Hydrogels at the Institut Biofunktionelle Polymermaterialien of the IPF
  • 2007: Doctoral thesis (Dr.-Ing.) in material science, Faculty of Mechanical Science and Engineering, Technische Universität Dresden
  • 2003-present: Scientific co-worker at Leibniz-Institut für Polymerforschung Dresden e.V. (IPF)/ Institut Biofunktionelle Polymermaterialien
  • 2001-2003: Process engineer, Advanced Micro Devices Saxony LLC & Co. KG, Dresden

Fields of work

  • multifunctional polymer materials for biomedical applications with special emphasis on glycosaminoglycan(GAG)-based hydrogels
  • synthetic and biohybrid matrices for tissue engineering applications
  • cell-instructive polymer coatings
  • cellulose thin films

Publications

  • Baumann, L. ; Prokoph, S. ; Gabriel, C. ; Freudenberg, U. ; Werner, C. ; Beck-Sickinger, A. G. A novel, biased-like SDF-1 derivative acts synergistically with star PEG -based heparin hydrogels and improves eEPC migration in vitro more Journal of Controlled Release 162 (2012) 68–75
  • Prokoph, S. ; Chavakis, E. ; Levental, K. ; Zieris, A. ; Freudenberg, U. ; Dimmeler, S. ; Werner, C. Sustained delivery of SDF-1a from heparin-based hydrogels to attract circulating pro-angiogenic cells more Biomaterials 33 (2012) 4792-4800
  • Freudenberg, U.; Sommer, J.-U.; Levental, K.; Welzel, P; Zieris, A.; Chwalek, K.; Schneider, K.; Prokoph, S.; Prewitz, M.; Dockhorn, R.; Werner, C. Using Mean Field Theory to Guide Biofunctional Materials Design more Advanced Functional Materials 22 (2012) 1391-1398
  • Chwalek, K. ; Levental, K. ; Tsurkan, M. ; Zieris, A. ; Freudenberg, U. ; Werner, C. Two-tier hydrogel degradation to boost endothelial cell morphogenesis more Biomaterials 32 (2011) 9649-9657
  • Zieris, A. ; Chwalek, K. ; Prokoph, S. ; Levental, K. ; Welzel, P. ; Freudenberg, U. ; Werner, C. Dual independent delivery of pro-angiogenic growth factors from starPEG-heparin hydrogels more Journal of Controlled Release 156 (2011) 28-36
  • Welzel, P. ; Prokoph, S. ; Zieris, A. ; Grimmer, M. ; Zschoche, St. ; Freudenberg, U. ; Werner, C. Modulating biofunctional starPEG heparin hydrogels by varying size and ratio of the constituents more Polymers [Open Access] 3 (2011) 602-620
  • Sommer, J.-U. ; Dockhorn, R. ; Welzel, P. ; Freudenberg, U. ; Werner, C. Swelling equilibrium of a binary polymer gel more Macromolecules 44 (2011) 981–986
  • Zieris, A. ; Prokoph, S. ; Levental, K. ; Welzel, P. ; Grimmer, M. ; Freudenberg, U. ; Werner, C. FGF-2 and VEGF functionalization of starPEG-heparin hydrogels to modulate biomolecular and physical cues of angiogenesis more Biomaterials 31 (2010) 7985-7994
  • Tsurkan, M. ; Chwalek, K. ; Levental, K. ; Freudenberg, U. ; Werner, C. Modular starPEG-heparin gels with bifunctional peptide linkers more Macromolecular Rapid Communications 31 (2010) 1529-1533
  • Müller, Y. ; Tot, I. ; Potthast, A. ; Rosenau, T. ; Zimmermann, R. ; Eichhorn, K.-J. ; Nitschke, C. ; Scherr, G. ; Freudenberg, U. ; Werner, C. The impact of esterification reactions on physical properties of cellulose thin films more Soft Matter 6 (2010) 3680-3684
  • Zimmermann, R. ; Freudenberg, U. ; Schweiß, R. ; Küttner, D. ; Werner, C. Hydroxide and hydronium ion adsorption - A survey more Current Opinion in Colloid and Interface Science 15 (2010) 196-202
  • Zieris, A. ; Prokoph, S. ; Welzel, P. ; Grimmer, M. ; Levental, K. ; Panyanuwat, W. ; Freudenberg, U. ; Werner, C. Analytical approaches to uptake and release of hydrogel-associated FGF-2 more Journal of Materials Science : Materials in Medicine 21 (2010) 915-923
  • Tsurkan, M. ; Levental, K. ; Freudenberg, U. ; Werner, C. Enzymatically degradable heparin-polyethylene glycol gels with controlled mechanical properties more Chemical Communications 46 (2010) 1141-1143
  • Lanfer, B. ; Hermann, A. ; Kirsch, M. ; Freudenberg, U. ; Reuner, U. ; Werner, C. ; Storch, A. Directed growth of adult human white matter stem cell-derived neurons on aligned fibrillar collagen more Tissue Engineering A 16 (2010) 1103-1113
  • Grombe, R. ; Gouzy, M.-F. ; Freudenberg, U. ; Pompe, T. ; Zschoche, St. ; Simon, F. ; Eichhorn, K.-J. ; Janke, A. ; Voit, B. ; Werner, C. Sulfated cellulose thin films with antithrombin affinity more eXPRESS Polymer Letters 3 (2009) 733-742
  • Welzel, P. ; Nitschke, M. ; Freudenberg, U. ; Zieris, A. ; Götze, T. ; Valtink, M. ; Engelmann, K. ; Werner, C. : Polymer Hydrogels to Enable New Medical Therapies more Springer 6 (2009) 249-266
  • Lanfer, B. ; Seib, P. ; Freudenberg, U. ; Stamov, D. ; Bley, Th. ; Bornhäuser, M. ; Werner, C. The growth and differentiation of mesemchymal stem and progenitor cells cultured on aligned collagen matrices more Biomaterials 30 (2009) 5950-5958
  • Freudenberg, U. ; Hermann, A. ; Welzel, P. ; Stirl, K. ; Schwarz, S. ; Grimmer, M. ; Zieris, A. ; Panyanuwat, W. ; Zschoche, St. ; Meinhold, D. ; Storch, A. ; Werner, C. A starPEG-heparin hydrogel platform to aid cell replacement therapies for neurodegenerative diseases more Biomaterials 30 (2009) 5049-5060
  • Lanfer, B. ; Freudenberg, U. ; Zimmermann, R. ; Stamov, D. ; Körber, V. ; Werner, C. Aligned fibrillar collagen matrices obtained by shear flow deposition more Biomaterials 29 (2008) 3888-3895
  • Freudenberg, U. ; Zimmermann, R. ; Schmidt, K. ; Behrens, S.-H. ; Werner, C. Charging and swelling of cellulose films more Journal of Colloid and Interface Science 309 (2007) 360-365
  • Freudenberg, U. ; Behrens, S.-H. ; Welzel, P. ; Müller, M. ; Grimmer, M. ; Salchert, K. ; Taeger, T. ; Schmidt, K. ; Pompe, W. ; Werner, C. Electrostatic interactions modulate the conformation of collagen I more Biophysical Journal 92 (2007) 2108-2119
  • Grombe, R. ; Gouzy, M.-F. ; Maitz, M.F. ; Freudenberg, U. ; Zschoche, St. ; Simon, F. ; Pompe, T. ; Sperling, C. ; Werner, C. Sulfated glycopolymer thin films - preparation, characterization, and biological activity more Macromolecular Bioscience 7 (2007) 195-200
  • Freudenberg, U. ; Zschoche, St. ; Simon, F. ; Janke, A. ; Schmidt, K. ; Behrens, S.-H. ; Auweter, H. ; Werner, C. Covalent Immobilization of Cellulose Layers onto Maleic Anhydride Copolymer Thin Films more Biomacromolecules 6 (2005) 1628-1634