Dr. Petra Welzel

Personal Homepage

Institute of Biofunctional Polymer Materials

+49 351 4658 584 +49 351 4658 533 welzel@ipfdd.de

Fields of Work

development of cell-instructive macroporous and multiphasic hydrogel materials for new therapeutic concepts as well as for advanced tissue and disease models;
adsorption of proteins at solid/liquid interfaces

Publications

Grundke, K. ; Pöschel, K. ; Synytska, A. ; Frenzel, R. ; Drechsler, A. ; Nitschke, M. ; Cordeiro, A. L. ; Uhlmann, P. ; Welzel, P. Experimental studies of contact angle hysteresis phenomena on polymer surfaces - Toward the understanding and control of wettability for different applications more Advances in Colloid and Interfaces Science 222 (2015) 350-376
Zieris, A. ; Dockhorn, R. ; Röhrich, A. ; Zimmermann, R. ; Müller, M. ; Welzel, P. ; Tsurkan, M. ; Sommer, J.-U. ; Freudenberg, U. ; Werner, C. Biohybrid networks of selectively desulfated glycosaminoglycans for tunable growth factor delivery more Biomacromolecules 15 (2014) 4439-446
Welzel, P. ; Friedrichs, J. ; Grimmer, M. ; Vogler, S. ; Freudenberg, U. ; Werner, C. Cryogel micromechanics unraveled by atomic force microscopy-based nanoindentation more Advanced Healthcare Materials 3 (2014) 1849-1853
König, U. ; Lode, A. ; Welzel, P. ; Ueda, Y. ; Knaack, S. ; Henß, A. ; Hauswald, A. ; Gelinsky, M. Heparinization of a biomimetic bone matrix: integration of heparin during matrix synthesis versus adsorption of heparin during matrix synthesis versus adsorptive post surface modification more Journal of Materials Science : Materials in Medicine 25 (2014) 607-621
Joly, P. ; Duda, G. N. ; Schöne, M. ; Welzel, P. ; Freudenberg, U. ; Werner, C. ; Petersen, A. Geometry-driven cell organization determines tissue growths in scaffold pores: Consequences for fibronectin organization more PLoS ONE 8 (2013) e73545
Zieris, A. ; Werner, C. ; Prokoph, S. ; Levental, K. ; Welzel, P. ; Chwalek, K. ; Schneider, K. ; Freudenberg, U. Sustainable growth factor delivery through affinity-based adsorption to star PEG-heparin hydrogels more American Chemical Society 1120 (2012) Chapter 24, 525-541
Welzel, P. ; Grimmer, M. ; Renneberg, C. ; Naujox, L. ; Zschoche, St. ; Freudenberg, U. ; Werner, C. Macroporous starPEG-heparin cryogels more Biomacromolecules 13 (2012) 2349-2358
Freudenberg, U.; Sommer, J.-U.; Levental, K.; Welzel, P; Zieris, A.; Chwalek, K.; Schneider, K.; Prokoph, S.; Prewitz, M.; Dockhorn, R.; Werner, C. Using Mean Field Theory to Guide Biofunctional Materials Design more Advanced Functional Materials 22 (2012) 1391-1398
Polikarpov, N. ; Appelhans, D. ; Welzel, P. ; Kaufmann, A. ; Dhanapal, P. ; Bellmann, C. ; Voit, B. Tailoring uptake and release of ATP by dendritic glycopolymer/PNIPAAm hydrogel hybrids: first approaches towards multicompartment release systems more New Journal of Chemistry 36 (2012) 438-451
Zieris, A. ; Chwalek, K. ; Prokoph, S. ; Levental, K. ; Welzel, P. ; Freudenberg, U. ; Werner, C. Dual independent delivery of pro-angiogenic growth factors from starPEG-heparin hydrogels more Journal of Controlled Release 156 (2011) 28-36
Welzel, P. ; Prokoph, S. ; Zieris, A. ; Grimmer, M. ; Zschoche, St. ; Freudenberg, U. ; Werner, C. Modulating biofunctional starPEG heparin hydrogels by varying size and ratio of the constituents more Polymers [Open Access] 3 (2011) 602-620
Sommer, J.-U. ; Dockhorn, R. ; Welzel, P. ; Freudenberg, U. ; Werner, C. Swelling equilibrium of a binary polymer gel more Macromolecules 44 (2011) 981–986
Zieris, A. ; Prokoph, S. ; Levental, K. ; Welzel, P. ; Grimmer, M. ; Freudenberg, U. ; Werner, C. FGF-2 and VEGF functionalization of starPEG-heparin hydrogels to modulate biomolecular and physical cues of angiogenesis more Biomaterials 31 (2010) 7985-7994
Zieris, A. ; Prokoph, S. ; Welzel, P. ; Grimmer, M. ; Levental, K. ; Panyanuwat, W. ; Freudenberg, U. ; Werner, C. Analytical approaches to uptake and release of hydrogel-associated FGF-2 more Journal of Materials Science : Materials in Medicine 21 (2010) 915-923
Welzel, P. ; Nitschke, M. ; Freudenberg, U. ; Zieris, A. ; Götze, T. ; Valtink, M. ; Engelmann, K. ; Werner, C. : Polymer Hydrogels to Enable New Medical Therapies more Springer 6 (2009) 249-266
Freudenberg, U. ; Hermann, A. ; Welzel, P. ; Stirl, K. ; Schwarz, S. ; Grimmer, M. ; Zieris, A. ; Panyanuwat, W. ; Zschoche, St. ; Meinhold, D. ; Storch, A. ; Werner, C. A starPEG-heparin hydrogel platform to aid cell replacement therapies for neurodegenerative diseases more Biomaterials 30 (2009) 5049-5060
Gelinsky, M. ; Welzel, P. ; Simon, P. ; Bernhardt, A. ; König, U. Porous three-dimensional scaffolds made of mineralised collagen: preparation and properties of a biomimetic nanocomposite material for tissue engineering of bone more Chemical Engineering Journal 137 (2008) 84-96
Freudenberg, U. ; Behrens, S.-H. ; Welzel, P. ; Müller, M. ; Grimmer, M. ; Salchert, K. ; Taeger, T. ; Schmidt, K. ; Pompe, W. ; Werner, C. Electrostatic interactions modulate the conformation of collagen I more Biophysical Journal 92 (2007) 2108-2119
Klose, T. ; Welzel, P. ; Werner, C. Protein adsorption from flowing solutions on pure and maleic acid copolymer modified glass particles more Colloids and Surfaces B: Biointerfaces 51 (2006) 1-9
Brandes, N. ; Welzel, P. ; Werner, C. ; Kroh, L.W. Adsorption-induced conformational changes of proteins onto ceramic particles: Differential scanning calorimetry and FTIR analysis more Journal of Colloid and Interface Science 299 (2006) 56-69
Schweiß, R. ; Welzel, P. ; Knoll, W. ; Werner, C. Assembly modulates dissociation: electrokinetic experiments reveal peculiarities of the charge formation at monolayer films more Chemical Communications (2005) 256-258
Schweiß, R. ; Pleul, D.Pleul ; Simon, F. ; Janke, A. ; Welzel, P. ; Voit, B. ; Knoll, W. ; Werner, C. Electrokinetic Potentials of Binary Self-Assembled Monolayers on Gold: Acid-Base Reactions and Double Layer Structure more Journal of Physical Chemistry / B 108 (2004) 2910-2917
Schönhoff, M. ; Larsson, A. ; Welzel, P. ; Kuckling, D. Thermoreversible Polymers Adsorbed to Colloidal Silica: A 1H NMR and DSC Study of the Phase Transition in Confined Geometry more Journal of Physical Chemistry / B 106 (2002) 7800-7808
Welzel, P. ; Rauwolf, C. ; Yudin, A. ; Grundke, K. Influence of Aqueous Electrolytes on the Wetting Behavior of Hydrophobic Solid Polymers - Low-Rate Dynamic Liquid/Fluid Contact Angle Measurements Using Axisymmetric Drop Shape Analysis more Journal of Colloid and Interface Science 252 (2002) 101-108
Welzel, P. Investigation of adsorption-induced structural changes of proteins at solid/liquid interfaces by differential scanning calorimetry more Thermochimica Acta 382 (2002) 175-188