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Paper "Glycosaminoglycan concentration and sulfation patterns of biohybrid polymer matrices direct microvascular network formation and stability" published
The new paper Glycosaminoglycan concentration and sulfation patterns of biohybrid polymer matrices direct microvascular network formation and stability by Yanuar Dwi Putra Limasale, Maximilian Fusenig, Marten Samulowitz, Passant Atallah, Jana Sievers, Nicholas Dennison, Uwe Freudenberg, Jens Friedrichs, and Carsten Werner adapts modular starPEG-GAG hydrogels with varying glycosaminoglycan (GAG) concentrations and sulfation patterns to explore their effects on microvascular network formation. Their research reveals that hydrogels with low concentrations of fully sulfated GAGs or high concentrations of moderately desulfated GAGs effectively support the formation of extensive and long-term stable vascular networks. This provides insights into designing precision biomaterials for improved vascularization in tissue models. The paper was published in Advanced Functional Materials. DOI: 10.1002/adfm.202411475
16.10.2024